Thursday, July 25, 2019
Recent cancer research Essay Example | Topics and Well Written Essays - 750 words
Recent cancer research - Essay Example Li C, Heidt DG, Dalerba P et .al (2007) has found that stem cells cause cancer in blood, breast, brain, prostate, ovary .The recent findings on the role of stem cells in causing cancer in pancreas also been stated in the study. In order to determine the mode of therapeutic intervention, it is quite critical to understand and define the specific stem cell where the cancer has originated. The study by Clarke, Michael F., Becker & Michael W (2008) has explained the potential of the stem cells in turning malignant and serves as the root of the cause of cancer. Further it has been stated that the stem cells promotes the growth of new cancer cells, and are considered as the origin of malignancy itself. In this regard these cells are termed as cancer stem cells. The study has also suggested the chances of these cells being normal stem cells at the origin or premature stage and they undergoing a malignant transformation in the growth stage. The authors urge the need for an accurate understanding on the transformation process in order to target the precise cancer stem cells in the process of cancer treatment or prevention. It is quite important to characterize and differentiate the normal human stem cells and the cancer initiating cells in order to have further knowledge on cancer therapy. A number of studies have evaluated the role of a number of antibodies on the Normal Stem Cells and the Malignant cells which is capable of Initiating Cancer. Donald J. Vander Griend, Wouter L. Karthaus, Susan Dalrymple, Alan Meeker, Angelo M. DeMarzo and John T. Isaacs have studied the role of the antibody CD 133 in Cancer. The study suggested that Androgen Receptor expressing prostate Cancer-Initiating Cells (CICs) is derived from malignantly transformed intermediate cells. (Donald J et. al, 2008). The importance of identification of stem cells has been asserted by Tuch, Bernard E. The study summarizes that the
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